Ambrosone, C. B., J. L. Freudenheim, et al. (1999). "Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer." Cancer Res 59(3): 602-6.

Bailey, L.B., J.F. Gregory . (1999)."Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement." J Nutr 129(5): 919-22

Bailey, L.B., J.F. Gregory. (1999). "Folate metabolism and requirements." J Nutr 129(4): 779-82

Borgstahl, G. E., H. E. Parge, et al. (1996). "Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface." Biochemistry 35(14): 4287-97.

Bosron, W.F., L. Ting-Kai (1986). "Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism." Hepatology 6(3): 502 - 510

Chango, A., F. Boisson, et al. (2000). "The effect of 677C-->T and 1298A-->C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects." Br J Nutr 83(6): 593-6.

Cheng, T., Z. Zhu et al. (2001). "Effects of multinutrient supplementation on antioxidant defense systems in healthy human beings." J Nutr Biochem 12(7): 388-395.

Chistyakov, D. A., Savost'anov, et al. (2001). "Polymorphisms in the Mn-SOD and EC-SOD genes and their relationship to diabetic neuropathy in type 1 diabetes mellitus." BMC Med Genet 2(1): 4.

Cosma, G., F. Crofts, et al. (1993). "Relationship between genotype and function of the human CYP1A1 gene." J Toxicol Environ Health 40(2-3): 309-16.

Crabb, D. W., H. J. Edenberg, et al. (1989). "Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant." J Clin Invest 83(1): 314-6.

Crofts, F., E. Taioli, et al. (1994). "Functional significance of different human CYP1A1 genotypes." Carcinogenesis 15(12): 2961-3.

Cronin K A, Krebs-Smith S M, Feuer E J, Troiano R P, Ballard-Barbash R. (2001 May). "Evaluating the impact of population changes in diet, physical activity, and weight status on population risk for colon cancer (United States)". Cancer Causes Control 12(4):305-16.

Dekou, V., P. Whincup, et al. (2001). "The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart study." Atherosclerosis 154(3): 659-66.

Department of Health, London; Stationary Office (2000). Committee on Medical Aspects of Food and Nutrition Policy. Folic acid and the prevention of disease.

Fennell, T. R., J. P. MacNeela, et al. (2000). "Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione S-transferase T1-null and M1-null genotypes." Cancer Epidemiol Biomarkers Prev 9(7): 705-12.

Fohr I.O., R. Prinz-Lnagenohl, et al. (2002). "10-Methyleneterahydrofolate reductase genotype determines the plasma homocysteine-lowering effect of supplementation with 5-methyltetrahydrofolate or folic acid in healthy young women." American Journal of Clinical Nutrition 75: 275 - 82

Fontana, R. J., K. S. Lown, et al. (1999). "Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P- glycoprotein levels in healthy volunteers." Gastroenterology 117(1): 89-98.

Fowke JH, Longcope C, Hebert JR. (2000) "Brassica Vegetable Consumption Shifts Estrogen Metabolism in Healthy Postmenopausal Women." Cancer Epidemiol Biomarkers Prev 9(8):773-779.

Gao, X., T. Albena, Dinkova-Kostova, P. Talalay (2001). "Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of sulforaphane." PNAS 98(26): 15221 - 15226.

Getahun SM, Chung FL.. (1999). "Conversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress." Cancer Epidemiology Biomarkers Preview 8(5): 447 - 451.

Giovannucci, E. (1999). "Nutritional factors in human cancers." Adv Exp Med Biol 472: 29-42.

Giovannucci, E. M.J. Stampfer, et al. (1998). "Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study." Annals of Internal Medicine 129: 517 – 524

Guyonnet, D., Belloir, C., Suschetet, M., Siess, M.H., Le Bon, A.M. (2001) Antimutagenic activity of organosulfur compounds from Allium is associated with phase II enzyme induction. Mut Res 496(1-2)135-142

Harada, S., D. P. Agarwal, et al. (2001). "Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorder." Alcohol Clin Exp Res 25(5 Suppl ISBRA): 71S-75S.

Inoue, K., T. Asao, et al. (2000). "Ethnic-related differences in the frequency distribution of genetic polymorphisms in the CYP1A1 and CYP1B1 genes in Japanese and Caucasian populations." Xenobiotica 30(3): 285-95.1.

Jacques, P. F., A. G. Bostom, et al. (1996). "Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations." Circulation 93(1): 7-9.

Kang, Z. C., S. J. Tsai, et al. (1999). "Quercetin inhibits benzo[a]pyrene-induced DNA adducts in human Hep G2 cells by altering cytochrome P-450 1A1 gene expression." Nutr Cancer 35(2): 175-9.

Lampe, J.W., C.Chen et al. (2000). "Modulation of human glutathione S-transferases by botanically defined vegetable diets." Cancer Epidemiology Biomarkers Preview 9(8):787-93.

Landi, S. (2000). "Mammalian class theta GST and differential susceptibility to carcinogens: a review." Mutat Res 463(3): 247-83.

Lanza, E; Schatzkin, A, Daston, C, Corle, D; Freedman, L, Ballard-Barbash, R, Caan, B, Lance, P, Marshall, J, Iber, F, Shike, M, Weissfeld, J, Slattery, M, Paskett, E, Mateski, D, Albert, P, and the PPT Study Group (2001). "Implementation of a 4-y, high-fiber, high-fruit-and-vegetable, low-fat dietary intervention: results of dietary changes in the Polyp Prevention Trial 1, 2" Am J Clin Nutr 74:387-401

Lin HJ, Probst-Hensch NM, Louie AD, Kau IH, Witte JS, Ingles SA, Frankl HD, Lee ER, Haile RW. (1998 Aug). "Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas." Cancer Epidemiol Biomarkers Prev 7(8):647-52.

London, S. J., J. M. Yuan, et al. (2000). "Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: a prospective study of men in Shanghai, China." Lancet 356(9231): 724-9.

Lutz, W. K. (1999). “Carcinogens in the diet vs overnutrition. Individual dietary habits, malnutrition, and genetic susceptibility modify carcinogenic potency and cancer risk.” Mutation Research 443: 251-258

Michaud DS, Spiegelman D, et al..(1999). "Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort." J Natl Cancer Inst 91(7): 605-13.

Miller MC 3rd, Mohrenweiser HW, Bell DA. (2001) “Genetic variability in susceptibility and response to toxicants.” Toxicol Lett 120(1-3):269-80

Nijhoff, W.A., T.P. Mulder et al. (1995). "Effects of consumption of brussels sprouts on plasma and urinary glutathione S-transferase class-alpha and -pi in humans." Carcinogenesis 16(4): 955-7.

Parke, D.V. (1999). "Antioxidants and disease prevention: mechanisms of action". Antioxidants in Human Health. CABI Publishing.

Perera, F. P. and I. B. Weinstein (2000). "Molecular epidemiology: recent advances and future directions." Carcinogenesis 21(3): 517-24.

Rozen, R. (2000). "Genetic modulation of homocysteinemia." Semin Thromb Hemost 26(3): 255-61.

Sandhu MS, White IR, McPherson K. (2001). “Systematic review of the prospective cohort studies on meat consumption and colorectal cancer risk: a meta-analytical approach.” Cancer Epidemiol Biomarkers Prev 10(5): 439-46

Schuppe HC, Wieneke P, Donat S, Fritsche E, Kohn FM, Abel J. (2000). “Xenobiotic metabolism, genetic polymorphisms and male infertility.” Andrologia 32(4-5): 255-62

Sinha R, Chow WH, Kulldorff M, Denobile J, Butler J, Garcia-Closas M, Weil R, Hoover RN, Rothman N. (1999). “Well-done, grilled red meat increases the risk of colorectal adenomas.” Cancer Res 59(17): 4320-4

Smith TJ, Yang CS. (2000). "Effect of organosulfur compounds from garlic and cruciferous vegetables on drug metabolism enzymes.” Drug Metabol Drug Interact 17(1-4):23-49

Spiteri, M. A., A. Bianco, et al. (2000). "Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation." Allergy 55(Suppl 61): 15-20.

Steinkellner H, Rabot S, Freywald C, Nobis E, Scharf G, Chabicovsky M, Knasmuller S, Kassie F. (2001). “Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.” Mutat Res 480-481: 285-97

Strange, R. C., M. A. Spiteri, et al. (2001). "Glutathione-S-transferase family of enzymes." Mutat Res 482(1-2): 21-6.

Sunder-Plassmann, G., M. Fodinger, et al. (2000). "Effect of high dose folic acid therapy on hyperhomocysteinemia in hemodialysis patients: results of the Vienna multicenter study." J Am Soc Nephrol 11(6): 1106-16.

Takeshita, T. and K. Morimoto (2000). "Accumulation of hemoglobin-associated acetaldehyde with habitual alcohol drinking in the atypical ALDH2 genotype." Alcohol Clin Exp Res 24(1): 1-7.

Ueland, P. M., S. Hustad, et al. (2001). "Biological and clinical implications of the MTHFR C677T polymorphism." Trends Pharmacol Sci 22(4): 195-201.

Vakevainen S, Tillonen J, Agarwal DP, Srivastava N, Salaspuro M. (2000). “High salivary acetaldehyde after a moderate dose of alcohol in ALDH2-deficient subjects: strong evidence for the local carcinogenic action of acetaldehyde.” Alcohol Clin Exp Res 22(4): 195-201

Van Iersel, M.L., H. Verhagen et al. (1999). "The role of biotransformation in dietary (anti)carcinogenesis." Mutation Research 443(1-2): 259-70.

Van Landeghem, G. F., P. Tabatabaie, et al. (1999). "Ethnic variation in the mitochondrial targeting sequence polymorphism of MnSOD." Hum Hered 49(4): 190-3.

Verhoeff, B. J., M. D. Trip, et al. (1998). "The effect of a common methylenetetrahydrofolate reductase mutation on levels of homocysteine, folate, vitamin B12 and on the risk of premature atherosclerosis." Atherosclerosis 141(1): 161-6.

Wang, X., B. Zuckerman, et al. (2002) "Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight." Journal of the American Medical Association 287(2): 195 - 202

Willett WC. (1995). ”Diet, nutrition, and avoidable cancer”. Environ Health Perspect 103(Suppl 8): 165-170

Williams JA, Martin FL, Muir GH, Hewer A, Grover PL, Phillips DH. (2000). “Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue.” Carcinogenesis 21(9): 1683-9.

Yamauchi M, Takeda K, Sakamoto K, Searashi Y, Uetake S, Kenichi And H, Toda G. (2001). “Association of polymorphism in the alcohol dehydrogenase 2 gene with alcohol-induced testicular atrophy.” Alcohol Clin Exp Res 25( Suppl 6): 16-8

Yokoyama A, Muramatsu T, Ohmori T, Yokoyama T, Okuyama K, Takahashi H, Hasegawa Y, Higuchi S, Maruyama K, Shirakura K, Ishii H. (1998). “Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics.” Carcinogenesis 19(8):1383-7

Zhao B, Seow A, Lee EJ, Poh WT, Teh M, Eng P, Wang YT, Tan WC, Yu MC, Lee HP. (2001). “Dietary isothiocyanates, glutathione S-transferase -M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore.” Cancer Epidemiol Biomarkers Prev 10(10): 1063-7

Zusterzeel PL, Nelen WL, Roelofs HM, Peters WH, Blom HJ, Steegers EA. (2000). “Polymorphisms in biotransformation enzymes and the risk for recurrent early pregnancy loss.” Mol Hum Reprod 6(5): 474-8

Last updated 19/12/2002